Vitals - Avastin slows advanced ovarian cancer's progress, report says: "For women with advanced cases of ovarian cancer, the drug Avastin adds about four months to the time it takes for the cancer to worsen, according to a new report.
Patients treated with Avastin in addition to chemotherapy had about 14 months before their advanced ovarian cancer progressed, compared to about 10 months for those in the study who were treated with chemotherapy and a placebo.
An early analysis of the trial's results was presented in June 2010 at the meeting of the American Society of Clinical Oncology; the complete report from the trial appeared Wednesday in the New England Journal of Medicine."
Avastin disappoints against ovarian cancer - Yahoo! News: "Avastin, the blockbuster drug that just lost approval for treating breast cancer, now looks disappointing against ovarian cancer, too. Two studies found it did not improve survival for most of these patients and kept their disease from worsening for only a few months, with more side effects.
The Genentech drug won approval in Europe last week for advanced ovarian cancer. But its maker has no immediate plans to seek the same approval in the United States. After talking with the Food and Drug Administration, "we do not believe the data will support approval" although no final decision has been made, said Charlotte Arnold, a spokeswoman for Genentech, part of the Swiss company Roche.
Results of the studies are in Thursday's New England Journal of Medicine.
In November, the FDA revoked Avastin's approval for breast cancer because it did not meaningfully extend life and can have serious side effects. Without approval, doctors can prescribe the drug but insurers may not pay. Treatment with it can cost $100,000 a year."
Patients treated with Avastin in addition to chemotherapy had about 14 months before their advanced ovarian cancer progressed, compared to about 10 months for those in the study who were treated with chemotherapy and a placebo.
An early analysis of the trial's results was presented in June 2010 at the meeting of the American Society of Clinical Oncology; the complete report from the trial appeared Wednesday in the New England Journal of Medicine."
Avastin disappoints against ovarian cancer - Yahoo! News: "Avastin, the blockbuster drug that just lost approval for treating breast cancer, now looks disappointing against ovarian cancer, too. Two studies found it did not improve survival for most of these patients and kept their disease from worsening for only a few months, with more side effects.
The Genentech drug won approval in Europe last week for advanced ovarian cancer. But its maker has no immediate plans to seek the same approval in the United States. After talking with the Food and Drug Administration, "we do not believe the data will support approval" although no final decision has been made, said Charlotte Arnold, a spokeswoman for Genentech, part of the Swiss company Roche.
Results of the studies are in Thursday's New England Journal of Medicine.
In November, the FDA revoked Avastin's approval for breast cancer because it did not meaningfully extend life and can have serious side effects. Without approval, doctors can prescribe the drug but insurers may not pay. Treatment with it can cost $100,000 a year."
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